Jessie is stresses with balancing her school load as she performs in her new band, Hot Sundae. In order to give her more energy, Jessie takes caffine pills to cope and slowly becomes addicted.

Brian and Stewie are accidently locked in a bank safe after hours. While waiting for someone to open the door, they have a meaningful conversation about life.

Paige notices her classmate Elle has blood coming down on her wrists and reports her to the school. Elle is not happy and comfronts Paige.

Aunt Cass begins to stress eat after picking up Tadashi and Hiro from the police station.

With the SATs coming up, Katie's experiences stress to the point that she suffers a panic attack.