Flanders explains to Lisa how he created the Jesus fish: through natural selection.

Mr. Burns makes a political campaign to rally the support of his peers. While doing so, he introduces his three-eyed fish, Blinky, then summons an actor portraying Charles Darwin to explain the concept of evolution.

Hank provides background information on the biologist who contributed to evolutionary history: Charles Darwin. He also explains the four principles of Darwin's idea of natural selection, which are variation, heritability, struggle for existence, and survival and reproduction rates. Key Words: Genetic Drift, Fitness, Variations of Phenotype, Heritable, The Struggle for Existence, Survival and Reproduction Rates

This clip describes how genetic mutations can lead to an animal's advantage in survival. Neil deGrasse Tyson talks about a Black bear that turns into a white bear because of a genetic mutation, which later became known as polar bears.

Sophie discusses how plants and animals need to compete in order to survive and the role that adaptations play in their ability to survive. She explains how several animals and bugs have adapted to become better suited to surviving in city environments.