The Bears go to the movie theater and watch a film titled, Germs. Iced Bear and Grizzly find the movie to be mildly entertaining, while Panda gets paranoid and scared of germs. While in the subway, Panda visualizes the germs in the environment and how they spread.

In George's dream, him and Gnocchi must work against the malicious germs that want to infect Professor Wiseman.

Frank gets ready to eat an egg he's prepared when a monkey at the zoo takes it from him. He fights with the monkey to get the egg back, and despite how filthy it has gotten, he eats it.

Beakman explains what allergies and allergens are. He talks about how the immune system causes the allergic reactions through the production of histamines. He uses a clip to show how a sneeze happens physiologically.

Panda and Clifford are having a fun time together when Clifford realizes Panda is using him to get close to his sister, Lucy. While running away from Panda, Clifford accidentally gets peanut butter all over himself, and he experiences a severe allergic reaction, causing his face to swell and his breathing to slow. Panda looks for the allergy pen to save Clifford and experiences a similar allergic reaction. Despite his condition, he manages to save Clifford, who in turn saves him with another allergy pen.