John Quincy Adams argues in favor of the African slaves in the United States v. The Amistad case in front of the Supreme Court. He displays fervent support for the abolition of slavery and asserts that the natural state of mankind is freedom, which contrasts with the South's view.

William takes Harriet to meet the Underground Railroad committee and officially inducts her as a committee member.

John talks about the Atlantic Slave Trade and descibes its process and conditions slaves underwent on boats and their life on farms and plantations in the Americas.

The narrator explains the Missouri Compromise, in which a compromise is reached about whether to make Missouri a slave or free state.

Key & Peele are slaves in an auction. At first, they do not want to be owned by another human being. After it becomes apparent that the white men are bidding on only the slaves on Lot A, Key & Peele start marketing themselves.