Leonard, Sheldon, and Penny are watching a cartoon and Penny is talking a lot. Leonard points out that Sheldon is using positive reinforcement to change Penny's behavior.

Dot tells Wakko to sit, and he starts acting like a dog and obeys her orders. She gives him treats in order to increase his willingness to take orders from her. In addition, Yakko and Dot educate Wakko on jargon. They discuss the jargon in Variety, a weekly American entertainment trade magazine, in particular.

Sheldon, Leonard, Howard, and Raj use negative reinforcement and positive punishment to keep themselves focused on their work. It doesn't exactly work as planned.

Everytime Jerry rings the bell, Butch the dog will come save him from Tom. But this isn't the case anymore when a law passes that dogs will always be on a leash.

Molly edits her video tutorial about how she trained her dog to find lost keys. This demonstrates the use of operant conditioning and the value of praise and reward for training pets.