Bananas makes a trip to the doctor when he has a stomachache. She tells him that he needs to eat a variety of foods, instead of just bananas. You need to eat from all of the food groups, so you can get all the necessary nutrients.
A visit to Dr. Grizzly's office in the midst of their preparation for the race shows Brother, Sister, and Papa that they should pay more attention to what kind of food they are putting into their bodies.
The group takes a boat ride through the small intestine, where the workers are not only singing about the intestine but are also part of an assembly line that illustrates the small intestine's function: the digestion and absorption of food.
While in the middle of its boat ride, the group encounters the sexually transmitted infection, gonorrhea. Before destroying gonorrhea with a lit match, Poncho alludes to a symptom of the infection: a burning sensation during urination.
Alex, Marty, Melman, and Gloria attempt to fit into the wild after having been raised in the New York City Zoo. During a performance to the Madagascar monkeys, Alex is suddenly overwhelmed by his hunger. He visualizes the audience members as the steaks that he was fed in the zoo and attacks his zebra friend, Marty. The monkeys inform the group that Alex is different from them since he needs meat to survive, and they are his food.